Tirap ELISA Kit for Mouse(Mus musculus) | EIAab.comTirap ELISA Kit for Mouse(Mus musculus)

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Tirap (Gene name),

Toll/interleukin-1 receptor domain-containing adapter protein (Protein name ), TIRAP_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Tirap(Mal);

Protein name:

Toll/interleukin-1 receptor domain-containing adapter protein(TIR domain-containing adapter protein);

Alternative:

MyD88 adapter-like protein;Adaptor protein Wyatt;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with BMX and TBK1 (By similarity). Homodimer. Also forms heterodimers with MyD88. Binds to TLR4 and IRAK2 via their respective TIR domains. Binds to PKR. Does not interact with IRAK1-1, nor TLR9.

Function:

Adapter involved in the TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response (By similarity). Positively regulates the production of TNF-alpha and interleukin-6.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

241

Sequence:

50:

100:

150:

200:

241:

GLSRAAYPPE | LRFMYYVDGR | GKDGGFYQVK | EAVIHYLETL | S

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q99JY1

KEGG:

mmu:117149

String:

Q99JY1

UniGene:

Mm.23987

Pfam:

PF13676

Pfam:

PF01582

Uniprot:

Q99JY1

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ELISA Kit for Mouse TIR domain-containing adapter protein

Cat.:

E4819h

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Manual:

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Packing:

96T

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ELISA Kit for Mouse TIR domain-containing adapter protein

Cat.:

E4819m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse TIR domain-containing adapter protein

Cat.:

U4819m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse TIR domain-containing adapter protein

Cat.:

U4819h

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse TIR domain-containing adapter protein

Cat.:

P4819Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse TIR domain-containing adapter protein

Cat.:

P4819Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse TIR domain-containing adapter protein

Protein for Mouse TIR domain-containing adapter protein

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"TIRAP: an adapter molecule in the Toll signaling pathway."
Horng T. , Barton G.M. , Medzhitov R.
Nat. Immunol.2:835-841(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: C57BL/6.
2.

"Characterization and structural analysis of TIR domain-containing adaptor protein Wyatt."
Kirk P.B. , Pereira J.P. , Bazan J.F.
Submitted (2001-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Mammary gland.
4.

"Role for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/Akt."
Troutman T.D. , Hu W. , Fulenchek S. , Yamazaki T. , Kurosaki T. , Bazan J.F. , Pasare C.
Proc. Natl. Acad. Sci. U.S.A.109:273-278(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PIK3AP1

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